Direct clinico-histological correlation of parapapillary chorioretinal atrophy.
نویسندگان
چکیده
منابع مشابه
Direct clinico-histological correlation of parapapillary chorioretinal atrophy.
Parapapillary chorioretinal atrophy is a morphological feature of glaucomatous optic nerve damage since it occurs more often and is larger in glaucomatous eyes than in normal eyes. This study was undertaken to find the histological correlation. Optic disc photographs and histological sections through the optic disc of 21 human eyes enucleated because of malignant uveal melanoma were morphometri...
متن کاملParapapillary chorioretinal atrophy in normal and glaucoma eyes. II. Correlations.
The parapapillary chorio-pigment-epithelio-retinal atrophy in glaucomatous eyes is significantly larger than in normal eyes. In a previous study its area and frequency have been measured in 582 eyes of 321 patients with chronic primary open-angle glaucoma and in 390 eyes of 231 normal subjects. In the current study the parapapillary changes were correlated with intrapapillary morphometric data ...
متن کاملParapapillary Atrophy: Histological Gamma Zone and Delta Zone
BACKGROUND To examine histomorphometrically the parapapillary region in human eyes. METHODOLOGY/PRINCIPAL FINDINGS The histomorphometric study included 65 human globes (axial length:21-37 mm). On anterior-posterior histological sections, we measured the distance Bruch's membrane end (BME)-optic nerve margin ("Gamma zone"), BME-retinal pigment epithelium (RPE) ("Beta zone"), BME-beginning of n...
متن کاملMicroglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma.
BACKGROUND Microglia, the macrophages and immune surveillance cells of the central nervous system, are quiescent normally but become activated in injured neural tissue. We have determined the distribution and potential participation of microglia in glaucomatous optic nerve degeneration. METHODS Microglia were localized by immunohistochemistry on paraffin sections of age-matched normal and gla...
متن کاملParapapillary chorioretinal atrophy in normal and glaucoma eyes. I. Morphometric data.
Glaucomatous optic nerve damage is associated with alterations of the intra- and parapapillary optic disc area. We measured and compared the parapapillary region in 582 eyes of 321 patients suffering from chronic primary open-angle glaucoma and in 390 eyes of 231 normal subjects. Only one randomly assessed eye per patient and subject was taken for statistical analysis. Highly mopic eyes with a ...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1993
ISSN: 0007-1161
DOI: 10.1136/bjo.77.2.103